Outcomes of a Postexposure Prophylaxis Program at the Korle-Bu Teaching Hospital in Ghana: A Retrospective Cohort Study.
Identifieur interne : 001639 ( Main/Exploration ); précédent : 001638; suivant : 001640Outcomes of a Postexposure Prophylaxis Program at the Korle-Bu Teaching Hospital in Ghana: A Retrospective Cohort Study.
Auteurs : Raymond A. Tetteh [Oman] ; Edmund T. Nartey [Ghana] ; Margaret Lartey [Ghana] ; Aukje K. Mantel-Teeuwisse [Pays-Bas] ; Hubert G M. Leufkens [Pays-Bas] ; Priscilla A. Nortey [Ghana] ; Alexander N O. Dodoo [Ghana]Source :
- Journal of the International Association of Providers of AIDS Care [ 2325-9574 ]
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Agents antiVIH (administration et posologie), Exposition professionnelle (), Femelle, Ghana (épidémiologie), Humains, Hôpitaux d'enseignement (), Incidence, Infections à VIH (), Infections à VIH (épidémiologie), Jeune adulte, Mâle, Personnel de santé (), Prophylaxie après exposition (), Études rétrospectives.
- MESH :
- administration et posologie : Agents antiVIH.
- épidémiologie : Ghana, Infections à VIH.
- Adolescent, Adulte, Adulte d'âge moyen, Exposition professionnelle, Femelle, Humains, Hôpitaux d'enseignement, Incidence, Infections à VIH, Jeune adulte, Mâle, Personnel de santé, Prophylaxie après exposition, Études rétrospectives.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- Adolescent, Adult, Anti-HIV Agents (administration & dosage), Female, Ghana (epidemiology), HIV Infections (epidemiology), HIV Infections (prevention & control), Health Personnel (statistics & numerical data), Hospitals, Teaching (statistics & numerical data), Humans, Incidence, Male, Middle Aged, Occupational Exposure (prevention & control), Occupational Exposure (statistics & numerical data), Post-Exposure Prophylaxis (statistics & numerical data), Retrospective Studies, Young Adult.
- MESH :
- chemical , administration & dosage : Anti-HIV Agents.
- geographic , epidemiology : Ghana.
- epidemiology : HIV Infections.
- prevention & control : HIV Infections, Occupational Exposure.
- statistics & numerical data : Health Personnel, Hospitals, Teaching, Occupational Exposure, Post-Exposure Prophylaxis.
- Adolescent, Adult, Female, Humans, Incidence, Male, Middle Aged, Retrospective Studies, Young Adult.
Abstract
The risk for occupational exposure to HIV is a serious public health problem that is well characterized in the developed world, but less so in the developing countries such as Ghana. This study was undertaken to examine the characteristics of occupational exposure to HIV and the utilization of a risk assessment system (RAS)-based postexposure prophylaxis (PEP) among health care workers (HCWs) and health care students (HCSs) in the Korle-Bu Teaching Hospital (KBTH). During the study period (January 2005-December 2010), a total of 260 and 35 exposures were reported by HCWs and HCSs, respectively. Ward attendants reported the highest incidence rate of 6.46 of 100 person-years (P-Y). The incidence of high-risk exposures was 0.33 of 100 P-Y (n = 65); 60.0% occurred during a procedure of disposing of a needle and 24.6% during a cannula insertion. A total of 289 of the 295 individuals were administered PEP, of which 181 (62.6%) completed the 6-month follow-up testing schedule and none sero-converted. This shows that with a good RAS in place, it is possible to deploy an effective PEP program in a typical African teaching hospital like the KBTH in Accra, Ghana.
DOI: 10.1177/2325957413508321
PubMed: 24162616
Affiliations:
- Ghana, Oman, Pays-Bas
- Région du Grand Accra, Utrecht (province)
- Accra, Utrecht
- Université d'Utrecht, Université du Ghana
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Le document en format XML
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Nortey</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legon, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legon, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName><orgName type="university">Université du Ghana</orgName></affiliation></author><author><name sortKey="Dodoo, Alexander N O" sort="Dodoo, Alexander N O" uniqKey="Dodoo A" first="Alexander N O" last="Dodoo">Alexander N O. Dodoo</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Tropical Clinical Pharmacology & Therapeutics, University of Ghana Medical School, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Centre for Tropical Clinical Pharmacology & Therapeutics, University of Ghana Medical School, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName></affiliation></author></analytic><series><title level="j">Journal of the International Association of Providers of AIDS Care</title><idno type="ISSN">2325-9574</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Anti-HIV Agents (administration & dosage)</term><term>Female</term><term>Ghana (epidemiology)</term><term>HIV Infections (epidemiology)</term><term>HIV Infections (prevention & control)</term><term>Health Personnel (statistics & numerical data)</term><term>Hospitals, Teaching (statistics & numerical data)</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>Occupational Exposure (prevention & control)</term><term>Occupational Exposure (statistics & numerical data)</term><term>Post-Exposure Prophylaxis (statistics & numerical data)</term><term>Retrospective Studies</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Agents antiVIH (administration et posologie)</term><term>Exposition professionnelle ()</term><term>Femelle</term><term>Ghana (épidémiologie)</term><term>Humains</term><term>Hôpitaux d'enseignement ()</term><term>Incidence</term><term>Infections à VIH ()</term><term>Infections à VIH (épidémiologie)</term><term>Jeune adulte</term><term>Mâle</term><term>Personnel de santé ()</term><term>Prophylaxie après exposition ()</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Agents antiVIH</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>HIV Infections</term><term>Occupational Exposure</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Health Personnel</term><term>Hospitals, Teaching</term><term>Occupational Exposure</term><term>Post-Exposure Prophylaxis</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Ghana</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Female</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Exposition professionnelle</term><term>Femelle</term><term>Humains</term><term>Hôpitaux d'enseignement</term><term>Incidence</term><term>Infections à VIH</term><term>Jeune adulte</term><term>Mâle</term><term>Personnel de santé</term><term>Prophylaxie après exposition</term><term>Études rétrospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The risk for occupational exposure to HIV is a serious public health problem that is well characterized in the developed world, but less so in the developing countries such as Ghana. This study was undertaken to examine the characteristics of occupational exposure to HIV and the utilization of a risk assessment system (RAS)-based postexposure prophylaxis (PEP) among health care workers (HCWs) and health care students (HCSs) in the Korle-Bu Teaching Hospital (KBTH). During the study period (January 2005-December 2010), a total of 260 and 35 exposures were reported by HCWs and HCSs, respectively. Ward attendants reported the highest incidence rate of 6.46 of 100 person-years (P-Y). The incidence of high-risk exposures was 0.33 of 100 P-Y (n = 65); 60.0% occurred during a procedure of disposing of a needle and 24.6% during a cannula insertion. A total of 289 of the 295 individuals were administered PEP, of which 181 (62.6%) completed the 6-month follow-up testing schedule and none sero-converted. This shows that with a good RAS in place, it is possible to deploy an effective PEP program in a typical African teaching hospital like the KBTH in Accra, Ghana.</div></front></TEI><affiliations><list><country><li>Ghana</li><li>Oman</li><li>Pays-Bas</li></country><region><li>Région du Grand Accra</li><li>Utrecht (province)</li></region><settlement><li>Accra</li><li>Utrecht</li></settlement><orgName><li>Université d'Utrecht</li><li>Université du Ghana</li></orgName></list><tree><country name="Oman"><region name="Région du Grand Accra"><name sortKey="Tetteh, Raymond A" sort="Tetteh, Raymond A" uniqKey="Tetteh R" first="Raymond A" last="Tetteh">Raymond A. Tetteh</name></region></country><country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Nartey, Edmund T" sort="Nartey, Edmund T" uniqKey="Nartey E" first="Edmund T" last="Nartey">Edmund T. Nartey</name></region><name sortKey="Dodoo, Alexander N O" sort="Dodoo, Alexander N O" uniqKey="Dodoo A" first="Alexander N O" last="Dodoo">Alexander N O. Dodoo</name><name sortKey="Lartey, Margaret" sort="Lartey, Margaret" uniqKey="Lartey M" first="Margaret" last="Lartey">Margaret Lartey</name><name sortKey="Nortey, Priscilla A" sort="Nortey, Priscilla A" uniqKey="Nortey P" first="Priscilla A" last="Nortey">Priscilla A. Nortey</name></country><country name="Pays-Bas"><region name="Utrecht (province)"><name sortKey="Mantel Teeuwisse, Aukje K" sort="Mantel Teeuwisse, Aukje K" uniqKey="Mantel Teeuwisse A" first="Aukje K" last="Mantel-Teeuwisse">Aukje K. Mantel-Teeuwisse</name></region><name sortKey="Leufkens, Hubert G M" sort="Leufkens, Hubert G M" uniqKey="Leufkens H" first="Hubert G M" last="Leufkens">Hubert G M. Leufkens</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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